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Peplin secures approximately US$24m in additional financing

18 / 08 / 2008

Peplin, Inc. (ASX:PLI) today announced the successful arrangement of a private placement of common stock and warrants to raise approximately US$24.0 million (Placement). The financing will primarily fund Phase III of clinical development of PEP005 (ingenol mebutate) for actinic (solar)…

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Additional information lodged with FDA for US clinical trial

13 / 08 / 2008

Sunshine Heart, Inc. (ASX: SHC) has today lodged additional information with the US Food and Drug Administration (FDA) in support of the Company's Investigational Device Exemption (IDE) application for approval to undertake a US clinical trial of Sunshine Heart's innovative C-PulseTM heart…

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Sales contracts worth $2.3 million signed since 1 July 2008

12 / 08 / 2008

Highlights: $1.2 million contract signed for Phase III schizophrenia study In total, nine sales contracts signed since 1 July 2008, worth $2.3 million $3 million in revenue already locked in for FY 2009 CogState Ltd (ASX:CGS) today announced…

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Australian company Xenome presents Xen2174 data on relief of pain in cancer patients at international conference

01 / 08 / 2008

A new drug for the treatment of severe pain under development by Australian biotechnology company Xenome Limited ("Xenome") has shown promise for the relief of chronic pain in cancer patients in a Phase II clinical trial. Relief of pain in cancer patients continues to…

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KaloBios Initiates Phase 1/2 Trial of HumaneeredT Monoclonal Antibody KB001 for Treatment of Pseudomonas Infections in Mechanically Ventilated Patients

19 / 05 / 2008

KaloBios Pharmaceuticals, Inc., a privately held biopharmaceutical company, today announced the initiation of a Phase 1/2 clinical trial of KB001, a HumaneeredT, high-affinity antibody fragment that KaloBios is developing for the treatment of Pseudomonas aeruginosa infections. …

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Uptake Medical Announces Successful Completion of Patient Enrollment in Pilot Safety & Feasibility Clinical Trial for Patients with Heterogeneous Emphysema

16 / 05 / 2008

Uptake Medical announced today that it has completed patient enrolment in a phase I safety and feasibility clinical trial for the company's proprietary minimally invasive Bronchoscopic Thermal Vapor AblationT (BTVAT) treatment for patients suffering from heterogeneous emphysema with upper…

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Novasys Medical Secures $49.5 Million in Series D Financing to Expand Commercialization of its Renessar Treatment for Incontinence in Women

15 / 05 / 2008

Novasys Medical, Inc., a developer of innovative therapies in women's health, announced today that it has secured $49.5 million in Series D preferred stock financing. The round was led by Versant Ventures, with ThreeArch Partners and Skyline Ventures also participating as new investors. The…

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Underwritten rights issue to raise $5.4 million

05 / 05 / 2008

Sunshine Heart, Inc. (ASX: SHC) today announced the terms of an underwritten non-renounceable rights issue to raise $5.4 million. Under the rights issue, eligible shareholders will be invited to subscribe for 4 new shares for every 11 shares held at the record date at an offer price of 7…

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KaloBios Expands Senior Management Team -- Adds Project Management and Additional Business Development Expertise --

05 / 05 / 2008

KaloBios Pharmaceuticals, Inc., a privately held biopharmaceutical company, today announced two additions to its senior management team that significantly strengthen the company's project management and pharmaceutical business development expertise. Jeanne Y. Jew, previously Vice…

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KaloBios Completes Patient Dosing in its U.S. Phase 1 Trial of Its Third Drug Candidate, KB003 -- First HumaneeredT Anti-GM-CSF Monoclonal Antibody Part of Comprehensive Inflammation Development Program --

28 / 04 / 2008

KaloBios Pharmaceuticals, Inc., a privately held biopharmaceutical company, today announced that the company has completed dosing subjects in a U.S. Phase 1 clinical trial of its third drug candidate, KB003. The study is a placebo-controlled, single-dose, dose-escalation Phase 1 trial in…

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Portland Orthopaedics Share Purchase Plan closes

15 / 04 / 2008

Portland Orthopaedics Limited (ASX: PLD) closed its Share Purchase Plan ("SPP") on 9 April. The SPP raised $280k. A total of 3.7 million new shares will be allotted tomorrow. "We were pleased with the response to the SPP by our shareholders given market conditions and we…

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ChemGenex Reports Oral Bioavailability of Omacetaxine and Expands on Mechanism of Action

15 / 04 / 2008

ChemGenex Pharmaceuticals Limited (ASX:CXS and NASDAQ:CXSP) announced today that pre-clinical data characterizing the bioavailability and mechanism of action of omacetaxine mepesuccinate (formerly known as Ceflatoninr) were presented on Monday local time at the American Association of…

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C-Pulse abstract presented at ISHLT Meeting, Boston

08 / 04 / 2008

Sunshine Heart, Inc. (ASX:SHC) announced today that a presentation at 28th Annual Meeting of the International Society for Heart and Lung Transplantation (ISHLT) will highlight results from the first human trial of the Company's C-PulseT System, an implantable, non-blood contacting heart…

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New Therapies Fight Phantom Noises of Tinnitus

01 / 04 / 2008

Modern life is loud. The jolting buzz of an alarm clock awakens the ears to a daily din of trucks idling, sirens blaring, televisions droning, computers pinging and phones ringing - not to mention refrigerators humming and air-conditioners thrumming. But for the 12 million Americans who…

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ChemGenex Investigators Present Data on Clinical Activity of Omacetaxine in Imatinib-Resistant Chronic Myeloid Leukemia Patients with the T315I Mutation at International Leukemia Conference

01 / 04 / 2008

ChemGenex Pharmaceuticals (ASX: CXS, NASDAQ: CXSP) has announced interim results from its ongoing phase 2/3 trial of omacetaxine mepesuccinate (formerly known as Ceflatoninr) in chronic myeloid leukemia (CML) patients with the T315I mutation. The data continue to show an increase in the…

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KaloBios Initiates Phase 1/2 Trial of HumaneeredT Monoclonal Antibody KB001 for Treatment of Pseudomonas Infections in Cystic Fibrosis Patients

31 / 03 / 2008

KaloBios Pharmaceuticals, Inc., a privately held biopharmaceutical company, today announced the initiation of a Phase 1/2 clinical trial of KB001, a HumaneeredT, high-affinity antibody fragment that KaloBios is developing for the treatment of P. aeruginosa infections. The trial is being…

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ChemGenex Launches Multi-Site Omacetaxine Clinical Trial in AML Patients

11 / 03 / 2008

ChemGenex Pharmaceuticals (ASX: CXS, NASDAQ: CXSP) announced today that it has launched a new phase 2 study evaluating the use of omacetaxine mepesuccinate (formerly homoharringtonine, HHT) in refractory or relapsed acute myeloid leukemia (AML) patients who have failed intensive…

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KaloBios Initiates Phase 1/2 Trial of KB002 Engineered Monoclonal Antibody in Persistent Asthma

10 / 03 / 2008

KaloBios Pharmaceuticals, Inc., a privately held biopharmaceutical company, today announced the initiation of a Phase 1/2 clinical study of KB002, the company's anti-GM-CSF monoclonal antibody, as a potential treatment for persistent asthma. The blinded, placebo-controlled…

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PHARMAXIS' FIRST STEPS INTO CHINA

07 / 03 / 2008

Pharmaxis (ASX:PXS, NASDAQ:PXSL) today announced that a clinical trial application for Bronchitol to treat bronchiectasis has been accepted for evaluation by China's State Food and Drug Administration (SFDA). All pharmaceutical companies are required to undertake a study in a…

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Portland adopts innovative financing with NAB

27 / 02 / 2008

Portland Orthopaedics Limited (ASX:PLD) has finalised an innovative $1.25 million financing package with The National Australia Bank (nab). The cornerstone of the financing is an innovative asset leasing package whereby Portland's surgical instrument sets will qualify as a…

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Portland Orthopaedics appoints Australian distributor

26 / 02 / 2008

Portland Orthopaedics (ASX:PLD) has engaged Taylor Bryant Surgical Specialties Division of Lifehealthcare Pty Ltd to market and sell Portland's hip replacement products throughout Australia. The three-year agreement is effective immediately. Lifehealthcare is exclusive…

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Hatchtech appoints Stewart Washer chairman

18 / 12 / 2007

Strengthens commercial expertise for expansion of world class insect control technologies Anti-egg hatching technology company Hatchtech Pty Ltd has appointed Dr Stewart Washer as chairman of its board of directors. Dr Washer is best known for his past 15 years…

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Continued Advancement in Heart Failure Therapies

17 / 12 / 2007

Sunshine Heart, Inc. (ASX: SHC) welcomed Thoratec Corporation's (NASDAQ: THOR) achievement of another milestone in the market growth of heart failure therapies. A U.S. Food & Drug Administration (FDA) advisory panel recommended unanimously that the agency approve, with conditions, the U.S.…

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ChemGenex Investigators Report Omacetaxine Effective in Killing CML Stem Cells in Animal Model Studies

11 / 12 / 2007

Key Leukemia Protein Mcl-1 Preferentially Down-Regulated by Omacetaxine ChemGenex Pharmaceuticals (ASX: CXS, NASDAQ: CXSP) announced today that pre-clinical data characterizing the mechanism of action of omacetaxine mepesuccinate (formerly known as Ceflatoninr)…

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